PIPA587471

DcR3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587471-Each-of-1 In Stock ₹ 46,502.50

PIPA587471 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

DcR3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFRSF6B

Gene Alias

DcR3, Decoy receptor 3, decoy receptor 3 variant 1, decoy receptor 3 variant 2, decoy receptor for Fas ligand, DJ583P15.1.1, hCG_2044836, M68, M68E, OTTHUMP00000031583, TNF receptor superfamily member 6b, TNFRSF6B, TR6, tumor necrosis factor receptor superfamily member 6B, tumor necrosis factor receptor superfamily member 6b, decoy, tumor necrosis factor receptor superfamily, member 6b, decoy, UNQ186/PRO212

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8771

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.19 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

O95407

Gene Symbols

TNFRSF6B

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human TNFRSF6B (NP_0038141)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PLSTRVPGAE ECERAVIDFV AFQDISIKRL QRLLQALEAP EGWGPTPRAG RAALQLKLRR RLTELLGAQD GALLVRLLQA LRVARMPGLE RSVRERFLPV H Positive Samples: HT-29 Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms
  • Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas
  • Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C
  • elegans death receptor-3) protease family
  • A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6)
  • Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway
  • Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.