DHCR24 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA592446-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA592446 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
DHCR24
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Dhcr24
Gene Alias
2310076D10Rik, 24-dehydrocholesterol reductase, 3 beta-hydroxysterol delta 24-reductase, 3-beta-hydroxysterol delta-24 reductase, 3-beta-hydroxysterol delta-24-reductase, 5830417J06Rik, DCE, Delta(24)-sterol reductase, desmosterol-to-cholesterol enzyme, DHCR24, Diminuto/dwarf1 homolog, KIAA0018, mKIAA0018, Nbla03646, seladin 1, SELADIN1, seladin-1, selective AD indicator 1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1718, 298298, 74754
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.42 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q15392, Q5BQE6, Q8VCH6
Gene Symbols
Dhcr24
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 227-516 of human DHCR24 (NP_0555771)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AEIRIIPAKK YVKLRFEPVR GLEAICAKFT HESQRQENHF VEGLLYSLDE AVIMTGVMTD EAEPSKLNSI GNYYKPWFFK HVENYLKTNR EGLEYIPLRH YYHRHTRSIF WELQDIIPFG NNPIFRYLFG WMVPPKISLL KLTQGETLRK LYEQHHVVQD MLVPMKCLQQ ALHTFQNDIH VYPIWLCPFI LPSQPGLVHP KGNEAELYID IGAYGEPRVK HFEARSCMRQ LEKFVRSVHG FQMLYADCYM NREEFWEMFD GSLYHKLREK LGCQDAFPEV YDKICKAARH; Positive Samples: U-87MG, HT-29, PC-12, NCI-H460; Cellular Location: Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass membrane protein DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis
- This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane
- Missense mutations in this gene have been associated with desmosterolosis
- Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.