KIF14 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587769-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA587769 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
KIF14
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KIF14
Gene Alias
D1Ertd367e, E130203M01, KIAA0042, KIF14, kinesin family member 14, kinesin-like protein KIF14, MKS12, N-3 kinesin, truncated kinesin family member 14
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
360849, 381293, 9928
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.46 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
L0N7N1, Q15058
Gene Symbols
KIF14
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1399-1648 of human KIF14 (NP_0556901)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LENGNNKAAS VQEEFMDAVC DGVGLGMKIL LDSGLEKAKE LQHELFRQCT KNEVTKEMKT NAMGLIRSLE NIFAESKIKS FRRQVQEENF EYQDFKRMVN RAPEFLKLKH CLEKAIEIII SALKGCHSDI NLLQTCVESI RNLASDFYSD FSVPSTSVGS YESRVTHIVH QELESLAKSL LFCFESEESP DLLKPWETYN QNTKEEHQQS KSSGIDGSKN KGVPKRVYEL HGSSPAVSSE ECTPSRIQWV; Positive Samples: HeLa, HL-60; Cellular Location: Cytoplasm, Midbody, Nucleus, cytoskeleton, spindle This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins
- These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis
- In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis
- An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein
- Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells
- This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas
- Alternative splicing results in multiple transcript variants.