Angiogenin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589249-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA589249 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Angiogenin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ANG
Gene Alias
AI385586, ALS9, ANG, Ang1, Angiogenin, angiogenin ribonuclease 1, angiogenin, ribonuclease A family, member 1, angiogenin, ribonuclease, RNase A family, 5, angiogenin-1, epididymis luminal protein 168, HEL168, MGC22466, MGC71966, RAA1, Ribonuclease 5, ribonuclease A A1, ribonuclease A family member 5, RNase 5, RNASE4, RNASE5, Rnase5a
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11727, 283, 305843
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
2.79 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P03950, P21570
Gene Symbols
ANG
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-147 of human ANG (NP_0011361)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: QDNSRYTHFL TQHYDAKPQG RDDRYCESIM RRRGLTSPCK DINTFIHGNK RSIKAICENK NGNPHRENLR ISKSSFQVTT CKLHGGSPWP PCQYRATAGF RNVVVACENG LPVHLDQSIF RRP; Positive Samples: LO2, HeLa, NCI-H460, B cells, Mouse liver, Rat liver; Cellular Location: Nucleus, basement membrane, extracellular matrix, extracellular space, nucleolus Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels
- ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs
- It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton
- ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth
- Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9)
- Angiogenin is a genetic link between ALS and PD.