PKC beta-1,2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589331-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA589331 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PKC beta-1,2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PRKCB
Gene Alias
A130082F03Rik, PKCB, PKC-B, PKC-Beta, Prkcb, PRKCB1, Prkcb2, protein kinase C beta, protein kinase C beta I, protein kinase C beta II, protein kinase C beta type, protein kinase C beta-II, protein kinase C, beta, protein kinase C, beta 1, protein kinase C, beta 1 polypeptide
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18751, 25023, 5579
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.40 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P05771, P68403, P68404
Gene Symbols
PRKCB
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 260-340 of human PKC-beta (NP_9977001)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SFGISELQKA SVDGWFKLLS QEEGEYFNVP VPPEGSEANE ELRQKFERAK ISQGTKVPEE KTTNTVSKFD NNGNRDRMKL T Positive Samples: Mouse liver; Cellular Location: Cytoplasm, Membrane, Nucleus, Peripheral membrane protein Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol
- PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways
- PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters
- Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells
- PKC beta is one of the PKC family members
- This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption
- Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress
- Alternatively spliced transcript variants encoding distinct isoforms have been reported
- Isoform 1 uses an alternate exon at the 3' end compared to isoform 2, which includes a part of the coding region
- The resulting isoform 1 has a distinct and shorter C-terminus, as compared to isoform 2.