MBP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595823-Each-of-1 | In Stock | ₹ 47,392.50 |
PIPA595823 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,392.50
GST (18%): ₹ 8,530.65
Total Price: ₹ 55,923.15
Antigen
MBP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MBP
Gene Alias
20 kDa microtubule-stabilizing protein, C76307, golli mbp, Golli-mbp, Golli-MBP, myelin basic protein, Golli-Mbp, myelin basic protein, myelin basic protein S, Hmbpr, MBP, MBP S, Mbps, MGC99675, microtubule-stabilizing protein, mLd, MOBP, Myelin A1 protein, myelin basic protein, myelin basic protein Golli-mbp, myelin basic protein S, myelin deficient, myelin membrane encephalitogenic protein, Myelin P1 protein, myelin-associated oligodendrocyte basic protein, R75289, shi, shiverer, Unknown (protein for IMAGE:7984318), unnamed protein product
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17196, 24547, 4155
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
6.99 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P02686, P02688, P04370
Gene Symbols
MBP
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 80-165 of human Myelin Basic Protein (NP_0010202721)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AHPADPGSRP HLIRLFSRDA PGREDNTFKD RPSESDELQT IQEDSAATSE SLDVMASQKR PSQRHGSKYL ATASTMDHAR HGFLPR Positive Samples: NB4, SH-SY5Y, HL-60, HT-29, PC-3, PC-12, BT-474, Mouse brain; Cellular Location: Cytoplasmic side, Myelin membrane, Nucleus, Peripheral membrane protein The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system
- However, MBP-related transcripts are also present in the bone marrow and the immune system
- These mRNAs arise from the long MBP gene (otherwise called "eGolli-MBP"e) that contains 3 additional exons located upstream of the classic MBP exons
- Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products
- The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons
- They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence
- The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins
- This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.