Mast Cell Chymase Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596382-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA596382 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Mast Cell Chymase
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CMA1
Gene Alias
alpha-chymase, Chymase, chymase 1, chymase 1 preproprotein transcript E, chymase 1 preproprotein transcript I, chymase 1, mast cell, chymase, heart, chymase, mast cell, CMA1, CYH, CYM, mast cell, Mast cell chymase 1, mast cell protease 3, Mast cell protease 5, mast cell protease I, Mast cell protease III, MCP3P, Mcp5, Mcp-5, Mcpt3, Mcpt5, MCT1, mMCP-5, rMCP-3, rMCP-5, rMCP-III
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1215, 17228
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.51 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P21844, P23946
Gene Symbols
CMA1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 81-247 of human Mast Cell Chymase (CMA1) (NP_0018271)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: A-549, A-431, HT-29, MCF7, Mouse lung, Mouse small intestine; Cellular Location: Cytoplasmic granule Immunogen sequence: ITEEEDTWQK LEVIKQFRHP KYNTSTLHHD IMLLKLKEKA SLTLAVGTLP FPSQFNFVPP GRMCRVAGWG RTGVLKPGSD TLQEVKLRLM DPQACSHFRD FDHNLQLCVG NPRKTKSAFK GDSGGPLLCA GVAQGIVSYG RSDAKPPAVF TRISHYRPWI NQILQAN This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1
- It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides
- In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II
- Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure
- Thus, this gene product is a target for cardiovascular disease therapies
- This gene maps to 14q11
- 2 in a cluster of genes encoding other proteases.