NPAS2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595855-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595855 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NPAS2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Npas2
Gene Alias
Basic-helix-loop-helix-PAS protein MOP4, bHLHe9, Class E basic helix-loop-helix protein 9, member of PAS protein 4, member of PAS superfamily 4, MOP4, neuronal PAS domain protein 2, neuronal PAS domain-containing protein 2, Neuronal PAS2, NPAS2, PAS domain-containing protein 4, PASD4
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
316351, 4862
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.68 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q99743
Gene Symbols
Npas2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 45-240 of human NPAS2 (NP_0025092)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KTTVLEKVIG FLQKHNEVSA QTEICDIQQD WKPSFLSNEE FTQLMLEALD GFIIAVTTDG SIIYVSDSIT PLLGHLPSDV MDQNLLNFLP EQEHSEVYKI LSSHMLVTDS PSPEYLKSDS DLEFYCHLLR GSLNPKEFPT YEYIKFVGNF RSYNNVPSPS CNGFDNTLSR PCRVPLGKEV CFIATVRLAT PQFLKE Members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family are transcription factors that contain a bHLH DNA binding domain located amino-terminal to a PAS domain
- Neuronal PAS domain protein 2 (NPAS2, also designated PAS 4/MOP4) is a member of the bHLH-PAS family and the PAS superfamily
- NPAS2, which maps to chromosome 2p11.2-2q13, is expressed primarily in the neurons during the first week of postnatal development
- The pattern of NPAS2 expression temporally matches the development of learning and memory, and spatially matches the frontal association/limbic forebrain pathway
- NPAS2 may serve a regulatory role in the development and maintenance of long-term memory, and may be required for the processing of complex sensory information
- NPAS2 and MOP3 form a transcriptionally active heterodimer which binds to a CACGTGA-containing DNA element and drives transcription from a linked luciferase reporter gene.