NELF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA592264-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA592264 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NELF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NSMF
Gene Alias
HH9, Jac, Jacob, Jacob protein, Juxtasynaptic attractor of caldendrin on dendritic boutons protein, nasal embryonic LHRH factor, Nasal embryonic luteinizing hormone-releasing hormone factor, NELF, NMDA receptor synaptonuclear signaling and neuronal migration factor, NSMF
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26012, 56876
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
3.3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q6X4W1, Q99NF2
Gene Symbols
NSMF
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 226-505 of human NSMF (NP_0011244431)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: FQTATTTMQA NFRKHLRMVG SRRVKAQTFA ERRERSFSRS WSDPTPMKAD TSHDSRDSSD LQSSHCTLDE AFEDLDWDTE KGLEAVACDT EGFVPPKVML ISSKVPKAEY IPTIIRRDDP SIIPILYDHE HATFEDILEE IERKLNVYHK GAKIWKMLIF CQGGPGHLYL LKNKVATFAK VEKEEDMIHF WKRLSRLMSK VNPEPNVIHI MGCYILGNPN GEKLFQNLRT LMTPYRVTFE SPLELSAQGK QMIETYFDFR LYRLWKSRQH SKLLDFDDVL; Positive Samples: LO2, HT-29, 293T, BT-474, Mouse brain; Cellular Location: Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane, Nucleus, Nucleus envelope, Nucleus matrix, Nucleus membrane, Peripheral membrane protein, cell cortex, cytoskeleton, dendrite, postsynaptic cell membrane, postsynaptic density, synapse, synaptosome NELF (nasal embryonic luteinizing hormone-releasing hormone factor) is a 530 amino acid transcription factor involved in the migration of LHRH neurons, outgrowth of olfactory axons and suppression of transcription elongation
- NELF is found in the peripheral and central nervous system during embryonic development, and is highly expressed in adult testis, kidney and brain
- Known to couple NMDA receptor signaling to the nucleus, NELF knockdown impaired GnRH neuronal migration of NLT cells in vitro and the gene encoding NELF has been linked to the development of Idiopathic hypogonadotropic hypogonadism (IHH), a disorder resulting in impaired pubertal maturation and reproductive function.