Cofilin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595869-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA595869 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
Cofilin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CFL1
Gene Alias
18 kDa phosphoprotein, AA959946, CFL, Cfl1, CFL-1, Cof, COF1, cofilin, cofilin 1, cofilin 1 (non-muscle), cofilin 1, non-muscle, cofilin, non-muscle isoform, Cofilin1, Cofilin-1, cofilin-1-like protein, epididymis secretory protein Li 15, HEL-S-15, n-cofilin, p18
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1072, 12631, 29271
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.24 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P18760, P23528, P45592
Gene Symbols
CFL1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CFL1 (NP_0054981)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE EGKEILVGDV GQTVDDPYAT FVKMLPDKDC RYALYDATYE TKESKKEDLV; Positive Samples: HeLa, Jurkat, SH-SY5Y, MCF-7, Mouse brain, Mouse testis, Rat brain, Rat ovary; Cellular Location: Cell projection, Cytoplasm, Cytoplasmic side, Nucleus matrix, Peripheral membrane protein, cytoskeleton, lamellipodium membrane, ruffle membrane Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity
- Regulates actin cytoskeleton dynamics
- Important for normal progress through mitosis and normal cytokinesis
- Plays a role in the regulation of cell morphology and cytoskeletal organization
- Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation
- Required for neural tube morphogenesis and neural crest cell migration.