CKMT1B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596224-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA596224 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
CKMT1B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CKMT1B
Gene Alias
acidic-type mitochondrial creatine kinase, CKMT, CKMT1, CKMT1A, CKMT1B, Creatine kinase U-type, mitochondrial, creatine kinase, mitochondrial 1 (ubiquitous), creatine kinase, mitochondrial 1B, mia-CK, ubiquitous mitochondrial creatine kinase, UMTCK, U-MtCK
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1159
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
0.55 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P12532
Gene Symbols
CKMT1B
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human CKMT1B (NP_0662701)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MAGPFSRLLS ARPGLRLLAL AGAGSLAAGF LLRPEPVRAA SERRRLYPPS AEYPDLRKHN NCMASHLTPA VYARLCDKTT PTGWT; Positive Samples: Mouse brain, Mouse kidney, Rat brain; Cellular Location: Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine
- It belongs to the creatine kinase isoenzyme family
- It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes
- Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes
- Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis
- Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase
- Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.