PIPA595973

ABCG8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595973-Each-of-1 In Stock ₹ 45,968.50

PIPA595973 - Each of 1

₹ 45,968.50

In Stock

Quantity

1

Base Price: ₹ 45,968.50

GST (18%): ₹ 8,274.33

Total Price: ₹ 54,242.83

Antigen

ABCG8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Abcg8

Gene Alias

1300003C16Rik, ABCG8, AI114946, ATP binding cassette subfamily G member 8, ATP-binding cassette sub-family G member 8, ATP-binding cassette, subfamily G (WHITE), member 8, ATP-binding cassette, sub-family G (WHITE), member 8, ATP-binding cassette, subfamily G, member 8, GBD4, MGC142217, sterolin 2, Sterolin2, sterolin-2, STSL

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

64241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

2.47 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q9H221

Gene Symbols

Abcg8

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human ABCG8 (NP_0718821)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MAGKAAEERG LPKGATPQDT SGLQDRLFSS ESDNSLYFTY SGQPNTLEVR DLNYQVDLAS QVPWFEQLAQ FKMPWTSPSC QNSCELGIQN LSFKVRSGQM LAIIGSSGCG RASLLDVITG RGHGGKIKSG QIWINGQPSS PQLVRKCVAH VRQHNQLLPN LTVRETLAFI AQMRLPRTFS QAQRDKRVED VIAELRLRQC ADTRVGNMYV RGLSGGERRR VSIGVQLLWN PGILILDEPT SGLDSFTAHN LVKTLSRLAK GNRLVLISLH QPRSDIFRLF DLVLLMTSGT PIYLGAAQHM VQYFTAIGYP CPRYSNPADF; Positive Samples: A-549; Cellular Location: Membrane, Multi-pass membrane protein ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body
  • ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols
  • The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.