GNAI3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595990-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595990 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GNAI3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GNAI3
Gene Alias
87U6, AI158965, ARCND1, AW537698, G protein subunit alpha i3, g(i) alpha-3, Galphai3, GIP3A, GNAI3, Gnai-3, guanine nucleotide binding protein (G protein), alpha inhibiting 3, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3, guanine nucleotide binding protein, alpha inhibiting 3, Guanine nucleotide binding, protein, alpha inhibiting polypeptide 3, Guanine nucleotide-binding protein G(i) subunit alpha, guanine nucleotide-binding protein G(k) subunit alpha
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25643, 2773
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.64 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P08753, P08754
Gene Symbols
GNAI3
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GNAI3 (NP_0064871)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MGCTLSAEDK AAVERSKMID RNLREDGEKA AKEVKLLLLG AGESGKSTIV KQMKIIHEDG YSEDECKQYK VVVYSNTIQS IIAIIRAMGR LKIDFGEAAR; Positive Samples: A-431, Rat kidney; Cellular Location: Cell membrane, Cytoplasm, Lipid-anchor, Membrane, centrosome, cytoskeleton, microtubule organizing center Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors
- Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i
- e
- adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous
- In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively
- Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors
- Four distinct classes of Galpha subunits have been identified; these include Gs, Gi, Gq and Galpha 12/13
- The Gi class comprises all the known alpha subunits that are susceptible to pertussis toxin modifications, including Galpha i-1, Galpha i-2, Galpha i-3, Galpha o, Galpha t1, Galpha t2, Galpha z and Galpha gust
- Of these, the three Galpha i subtypes function to open atrial potassium channels.