ROR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596369-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA596369 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ROR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ROR2
Gene Alias
BDB, BDB1, mRor2, neurotrophic tyrosine kinase receptor-related 2, neurotrophic tyrosine kinase, receptor related 2, neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, receptor tyrosine kinase like orphan receptor 2, receptor tyrosine kinase-like orphan receptor 2, ROR2, Tyrosine-protein kinase transmembrane receptor ROR2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26564, 306782, 4920
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.43 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q01974, Q9Z138
Gene Symbols
ROR2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ROR2 (NP_0045512)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: APVVQEPRRI IIRKTEYGSR LRIQDLDTTD TGYYQCVATN GMKTITATGV LFVRLGPTHS PNHNFQDDYH EDGFCQPYRG IACARFIGNR TIYVDSLQMQ G; Positive Samples: U-87MG; Cellular Location: Cell membrane, Single-pass type I membrane protein ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors
- It is thought to be involved in the early formation of the chondrocytes and cartilage and growth plate development
- This Type I membrane protein is expressed at high levels during early embryonic development
- The expression levels drop strongly around day 16 and there are only very low levels in adult tissues
- Defects in ROR2 are a cause of brachydactyly type B1 (BDB1)
- BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails
- In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent
- Both fingers and toes are affected
- The thumbs and big toes are usually deformed
- Defects in ROR2 are a cause of recessive Robinow syndrome (RRS)
- RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance
- The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.