TIMM8A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597251-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA597251 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TIMM8A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TIMM8A
Gene Alias
DDP, Ddp1, deafness dystonia protein 1, Deafness dystonia protein 1 homolog, deafness/dystonia peptide, DFN1, DXHXS1274E, Fci-12, Mitochondrial import inner membrane translocase subunit Tim8 A, MTS, TIM8, Tim8a, Timm8a, Timm8a1, translocase of inner mitochondrial membrane 8 homolog a, translocase of inner mitochondrial membrane 8 homolog A (yeast), translocase of inner mitochondrial membrane 8 homolog a1, translocase of inner mitochondrial membrane 8 homolog A1 (yeast), translocase of inner mitochondrial membrane 8A1, X-linked deafness dystonia protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1678, 30058, 84383
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
2 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
O60220, Q9WVA1, Q9WVA2
Gene Symbols
TIMM8A, Timm8a1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human TIMM8A (NP_0040761)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MDSSSSSSAA GLGAVDPQLQ HFIEVETQKQ RFQQLVHQMT ELCWEKCMDK PGPKLDSRAE ACFVNCVERF IDTSQFILNR LEQTQKSKPV FSESLSD; Positive Samples: U-251MG, A-549, LO2, 293T, MCF-7, HeLa, Mouse liver, Mouse brain; Cellular Location: Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane
- Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane
- Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space
- The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins
- Probably necessary for normal neurologic development.