PIPA597264
TEP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597264-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA597264 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TEP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TEP1
Gene Alias
p230, p240, p80 homolog, p80 telomerase homolog, rTLP1, telomerase associated protein 1, telomerase protein 1, Telomerase protein component 1, telomerase-associated protein 1, Tep1, TLP1, Tp1, TROVE domain family, member 1, TROVE1, VAULT2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7011
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.82 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q99973
Gene Symbols
TEP1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2523-2627 of human TEP1 (NP_0090412)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TCRESDASMD SDASMDSEPT PHLKTRQRRK IHSGSVTALH VLPELLVTAS KDRDVKLWER PSMQLLGLFR CEGSVSCLEP WLGANSTLQL AVGDVQGNVY FLNWE; Positive Samples: DU145; Cellular Location: Chromosome, Nucleus, telomere Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes
- Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1)
- Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can μgtimately lead to telomere fusion and cell death
- High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TP1 do not correlate with malignancy
- At least two isoforms of TP1 are known to exist.