PIPA597917

CD223 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597917-Each-of-1 In Stock ₹ 46,947.50

PIPA597917 - Each of 1

₹ 46,947.50

In Stock

Quantity

1

Base Price: ₹ 46,947.50

GST (18%): ₹ 8,450.55

Total Price: ₹ 55,398.05

Antigen

CD223

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LAG3

Gene Alias

Activation-induced cytidine deaminase-linked autoimmunity protein, Aida, CD223, FDC, LAG3, LAG-3, Ly66, lymphocyte activating 3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Secreted lymphocyte activation gene 3 protein, sLAG 3, sLAG3, sLAG-3, soluble LAG 3lymphocyte activating 3, soluble LAG3

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3902

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Concentration

3 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.

P18627

Gene Symbols

LAG3

Immunogen

Recombinant Human Lymphocyte activation gene 3 protein (29-450AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).