PIPA599723

SS18 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599723-Each-of-1 In Stock ₹ 46,502.50

PIPA599723 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SS18

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SS18

Gene Alias

D130059H17; MGC116875; Protein SSXT; Protein SYT; SS18; SS18, nBAF chromatin remodeling complex subunit; Ssxt; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to X chromosome; synovial sarcoma-associated Ss18-alpha; SYT

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6760

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15532

Gene Symbols

SS18

Immunogen

A synthesized peptide derived from human SS18(Accession Q15532), corresponding to amino acid residues M1-D37.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total SYT
  • The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence
  • Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini
  • SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens
  • The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.