RB9052R1

GLUT-1 Rabbit Polyclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

GLUT-1

Classification

Polyclonal

Conjugate

Unconjugated

Immunogen

A synthetic peptide derived from C-terminal of human GLUT-1

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Prediluted

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

Polyclonal

Host Species

Rabbit

Quantity

1 mL

Research Discipline

Steroids Hormones and Growth Factors

Target Species

Human

Isotype

IgG

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Description

  • Description Glucose is fundamental to the metabolism of mammalian cells
  • Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling
  • GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast
  • GLUT-1 immunoreactivity in some cancers, including trans carcinoma of the urinary bladder, has been associated with aggressive behavior
  • Host Species: Rabbit Isotype: IgG Species Reactivity: Human and Rat
  • Others not tested
  • Epitope: C-terminal Immunogen: A synthetic peptide derived from C-terminal of human GLUT-1 Molecular Weight: 55 kDa, 45 kDa depending on the extent of glycosylation Positive Control: Rat brain lysate; Breast CA, squamous cell CA, nonsmall-cell lung CA and esophageal CA Cellular Localization: Membrane and focal cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence