ST1204100UL
MilliporeSigma™ anti-PGC-1alpha, Polyclonal
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ST1204100UL-Each-of-1 | In Stock | ₹ 55,165.76 |
ST1204100UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,165.76
GST (18%): ₹ 9,929.837
Total Price: ₹ 65,095.597
Antigen
PGC-1α
Classification
Polyclonal
Formulation
In 50mM PBS
Immunogen
A recombinant protein consisting of amino acids 1-120 of mouse PGC-1α
Regulatory Status
RUO
Test Specificity
Recognizes the ∽113kDa PGC-1α protein in BAT cells.
Content And Storage
≤ -70°C
Isotype
IgG
Applications
Immunoprecipitation
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
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Description
- Specifically detects PGC-1α Clone: in Human, Mouse, Rat samples, and it is validated for Immunoprecipitation PGC-1α is a co-activator of PPARα, PPARγ, and other transcription factors that regulate the transcriptonal program of adaptive thermogenesis in brown adipose tissue, hepatic/renal gluconeogenesis, and muscle fiber type switching
- The full length protein is detected at 113kDa and is induced in BAT by cold exposure, in liver and kidney by fasting, and in skeletal muscle by exercise
- Alternative splicing of the full length gene produces a 270 aa N-terminal splice variant that migrates at∽38kDa and is induced by the same physiological signals which induce expression of the full length protein
- The N-terminal PGC-1α splice variant is also subject to post translational modifications which alter its migration and apparent molecular weight.