ST1673100UG

MilliporeSigma™ anti-AFP Clone: 1G7,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ST1673100UG-Each-of-1 In Stock ₹ 47,081.00

ST1673100UG - Each of 1

₹ 47,081.00

In Stock

Quantity

1

Base Price: ₹ 47,081.00

GST (18%): ₹ 8,474.58

Total Price: ₹ 55,555.58

Antigen

AFP

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

ELISA, Immunoblot, Immunoblot, Immunocytochemistry

Clone

1G7

Formulation

In PBS, pH 7.2.

Immunogen

A recombinant polypeptide corresponding to amino acids of 500-610 human AFP, expressed as a GST fusion protein

Regulatory Status

RUO

Test Specificity

Recognizes the ∽70-75kDa AFP protein in HepG2 cells.

Content And Storage

−20°C

Isotype

IgG

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Description

  • Specifically detects AFP Clone: 1G7 in Human samples, and it is validated for ELISA, Immunocytochemistry, Immuno Blotting This gene encodes α-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life
  • α-fetoprotein expression in adults is often associated with hepatoma or teratoma
  • However, hereditary persistence of α-fetoprotein may also be found in individuals with no obvious pathology
  • The protein is thought to be the fetal counterpart of serum albumin, and the α-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
  • α-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin
  • The level of α-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.