ST1681200UL

MilliporeSigma™ anti-SIGIRR Clone: 3H8-2G3,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ST1681200UL-Each-of-1 In Stock ₹ 47,081.00

ST1681200UL - Each of 1

₹ 47,081.00

In Stock

Quantity

1

Base Price: ₹ 47,081.00

GST (18%): ₹ 8,474.58

Total Price: ₹ 55,555.58

Antigen

SIGIRR

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Unpurified

Regulatory Status

RUO

Test Specificity

Recognizes the ∽32kDa SIGIRR protein in HepG2 cells.

Content And Storage

−20°C

Applications

Immunoblot

Clone

3H8-2G3

Formulation

Undiluted ascites

Immunogen

Full-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Isotype

IgM

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Description

  • Specifically detects SIGIRR Clone: 3H8-2G3 in Human samples, and it is validated for Immuno Blotting The SIGIRR protein acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways
  • It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4
  • Its extracellular domain is known to interfere with the heterodimerization of Il1R1 and IL1RAP.