68-135-0

Tocris Bioscience™ Ibrutinib

Manufacturer: Fischer Scientific

CAS Number: 936563-96-1

Select a Size

Pack Size SKU Availability Price
Each of 1 68-135-0-Each-of-1 In Stock ₹ 82,058.00

68-135-0 - Each of 1

₹ 82,058.00

In Stock

Quantity

1

Base Price: ₹ 82,058.00

GST (18%): ₹ 14,770.44

Total Price: ₹ 96,828.44

Chemical Name or Material

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one

Synonym

Agammaglobulinaemia tyrosine kinase, AGMX1, ATKIMD1, B-cell progenitor kinase, BPK, Bruton agammaglobulinemia tyrosine kinase, Bruton tyrosine kinase, dominant-negative kinase-deficient Brutons tyrosine kinase, tyrosine-protein kinase

Molecular Formula

C25H24N6O2

Purity

98%

CAS

936563-96-1

Quantity

50 mg

Formula Weight

440.5

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Description

  • Selective for BTK against a screening panel of kinase enzymes Inhibits autophosphorylation of BTK, phosphorylation of PLCγ, and phosphorylation of ERK (IC50 of 11 nM, 29 nM and 13 nM, respectively) Induces cytotoxicity of chronic lymphocytic leukemia (CLL) cells Reduces clinical arthritis scores in a mouse model.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C