7110965

Tocris Bioscience™ DMXAA

mSTING agonist; induces antitumor immunological responses

Manufacturer: Fischer Scientific

CAS Number: 117570-53-3

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Chemical Name or Material

5,6-Dimethyl-9-oxo-9 H-xanthene-4-acetic acid

Target

STING Agonists

Formula Weight

282.29

CAS

117570-53-3

Molecular Formula

C17H14O4

Purity

99%

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Description

  • mSTING agonist; selective for mouse STING over human STING
  • Induces IFN-β and cytokine production from bone marrow-derived dendritic cells
  • Causes tumor regression following intratumoral administration in mouse tumor models
  • Induces an adaptive immune response to reduce systemic tumor growth and provides immunological memory against autologous tumor re-challenge
  • Also antiviral.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C