K1445

Thermo Scientific™ Tango™ ADORA1-blaU2OS Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1445-Each-of-1 In Stock ₹ 9,41,620.00

K1445 - Each of 1

₹ 9,41,620.00

In Stock

Quantity

1

Base Price: ₹ 9,41,620.00

GST (18%): ₹ 1,69,491.60

Total Price: ₹ 11,11,111.60

Accession Number

NM_000674.1

Cell State

Dividing Cells

Cytoplasmic Tail

Tail from AVPR2 GPCR

Gene Symbol

ADORA1A

Product Line

Tango™

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

U2OS

Druggable Target

GPCR

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ ADORA1-bla U2OS cells• Tango™ ADORA1-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ ADORA1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Population Status

Pool of Stable Cells

Quantity

2 x 106Cells

Target Entry

ADORA1

System Type

Tango™

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Description

  • The Tango™ ADORA1-bla U2OS cells contain the human Adenosine A1 receptor (ADORA1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
  • The Tango™ ADORA1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of NECA
  • In addition, Tango™ ADORA1-bla U2OS cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.