K1604

Thermo Scientific™ Tango™ ADRA2A-blaU2OS Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1604-Each-of-1 In Stock ₹ 9,35,390.00

K1604 - Each of 1

₹ 9,35,390.00

In Stock

Quantity

1

Base Price: ₹ 9,35,390.00

GST (18%): ₹ 1,68,370.20

Total Price: ₹ 11,03,760.20

Accession Number

NM_000681.2

Cell State

Dividing Cells

Cytoplasmic Tail

Tail from AVPR2 GPCR

Gene Symbol

ADRA2A

Product Line

Tango™

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

U2OS

Druggable Target

GPCR

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ ADRA2A-bla U2OS cells• Tango™ ADRA2A-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ ADRA2A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Population Status

Single Cell Clone Origin

Quantity

2 x 106Cells

Target Entry

ADRA2A

System Type

Tango™

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Description

  • The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
  • The Tango™ ADRA2A-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands
  • In addition, Tango™ ADRA2A-bla U2OS cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary for each product.