K1564
Thermo Scientific™ Tango™ CHRM2-blaU2OS Cells
Manufacturer: Thermo Scientific™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1564-Each-of-1 | In Stock | ₹ 9,41,620.00 |
K1564 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,41,620.00
GST (18%): ₹ 1,69,491.60
Total Price: ₹ 11,11,111.60
Accession Number
NM_000739.2
Cell State
Dividing Cells
Cytoplasmic Tail
Tail from GRPR GPCR
Gene Symbol
M2
Product Line
Tango™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
CHRM2, M2
System Type
Tango™
Assay Entry
Cell-based beta-arrestin recruitment
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ CHRM2-bla U2OS cells• Tango™ CHRM2-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ CHRM2-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method
Fluorescence
Population Status
Single Cell Clone Origin
Quantity
2 x 106Cells
Shipping Condition
Room Temperature
Cell Line
U2OS
Druggable Target
GPCR
Related Products
Description
- The Tango™ CHRM2-bla U2OS cells contain the human Cholinergic muscarinic 2 receptor (CHRM2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
- The Tango™ CHRM2-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Carbachol
- In addition, Tango™ CHRM2-bla U2OS cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.