K1576

Invitrogen™ Tango™ OPRK1-blaU2OS Cells

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1576-Each-of-1 In Stock ₹ 9,15,810.00

K1576 - Each of 1

₹ 9,15,810.00

In Stock

Quantity

1

Base Price: ₹ 9,15,810.00

GST (18%): ₹ 1,64,845.80

Total Price: ₹ 10,80,655.80

Accession Number

NM_000912

Cell State

Dividing Cells

Cytoplasmic Tail

Tail from AVPR2 GPCR

Gene Symbol

OPRK1

Product Line

Tango™

Reporter Gene

BLA (Beta-Lactamase)

Type

U2OS Cell

System Type

Tango™

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

K1576 Tango™ OPRK1-bla U2OS cells(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).Includes:• Tango™ OPRK1-bla U2OS cells• Tango™ OPRK1-bla U2OS Assay Protocol• Certificate of AnalysisStorage:The Tango™ OPRK1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Population Status

Pool of Stable Cells

Quantity

2 x 106cells

Target Entry

OPRK1

Cell Line

U2OS

Druggable Target

GPCR

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Description

  • The Tango™ OPRK1-bla U2OS cells contain the human Opiod Receptor Kappa 1 (OPRK1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
  • The Tango™ OPRK1-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands
  • In addition, Tango™ OPRK1-bla U2OS cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary for each product.