K1779

Thermo Scientific™ Tango™ CXCR4-blaU2OS Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1779-Each-of-1 In Stock ₹ 9,23,820.00

K1779 - Each of 1

₹ 9,23,820.00

In Stock

Quantity

1

Base Price: ₹ 9,23,820.00

GST (18%): ₹ 1,66,287.60

Total Price: ₹ 10,90,107.60

Accession Number

NM_003467.2

Cell State

Dividing Cells

Cytoplasmic Tail

Native Tail

For Use With (Application)

FRET

Population Status

Single Cell Clone Origin

Quantity

8 x 106Cells

Reporter Gene

BLA (Beta-Lactamase)

Type

U2OS Cell

System Type

Tango™

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ CXCR4-blaU2OS cells• Tango™ CXCR4-blaU2OS Assay Protocol• Certificate of AnalysisThe Tango™ CXCR4-blaU2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Gene Symbol

CXCR4

Product Line

GeneBLAzer™, Tango™

Readout

End Point

Target Entry

CXCR4

Cell Line

U2OS

Druggable Target

GPCR

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Description

  • The Tango™ CXCR4- bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 4 (CXCR4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR- bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase ( bla ) reporter gene under the control of a UAS response element
  • The Tango™ CXCR4- bla U2OS cells are functionally validated for Z' and EC 50 concentrations of SDF1α
  • In addition, Tango™ CXCR4- bla U2OS cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary
  • For Academic pricing please login or contact us at discoverysciences@invitrogen.com.