K1818
Thermo Scientific™ Tango™ M4-blaU2OS Cells
Manufacturer: Thermo Scientific™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1818-Each-of-1 | In Stock | ₹ 9,41,620.00 |
K1818 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,41,620.00
GST (18%): ₹ 1,69,491.60
Total Price: ₹ 11,11,111.60
Accession Number
NM_000741
Cell State
Dividing Cells
Cytoplasmic Tail
Native Tail
For Use With (Application)
FRET
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Product Line
GeneBLAzer™, Tango™
Readout
End Point
Type
U2OS Cell
System Type
Tango™
Assay Entry
Cell-based beta-arrestin recruitment
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ M4-bla U2OS cells• Tango™ M4-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ M4-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method
Fluorescence
Gene Symbol
M4
Population Status
Single Cell Clone Origin
Quantity
8 x 106Cells
Target Entry
M4
Cell Line
U2OS
Druggable Target
GPCR
Related Products
Description
- The Tango™ M4-bla U2OS cells contain the human Acetycholine (muscarinic) subtype 4 receptor (M4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
- The Tango™ M4-bla U2OS cells are functionally validated for Z' and EC50 concentrations of Carbachol
- In addition, Tango™ M4-bla U2OS cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary
- For Academic pricing please login or contact us at discoverysciences@invitrogen.com.