K1845

Thermo Scientific™ Tango™ GPR120S-blaU2OS Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1845-Each-of-1 In Stock ₹ 9,41,620.00

K1845 - Each of 1

₹ 9,41,620.00

In Stock

Quantity

1

Base Price: ₹ 9,41,620.00

GST (18%): ₹ 1,69,491.60

Total Price: ₹ 11,11,111.60

Accession Number

NM_181745.2

Cell State

Dividing Cells

Cytoplasmic Tail

Native Tail

For Use With (Application)

FRET

Human Protein Class

G-Protein Coupled Receptor (GPCR)

Product Line

Tango™

Readout

End Point

Type

U2OS Cell

System Type

Tango™

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D, and other materials are required separately; please refer to the protocol.Includes:• Tango™ GPR120S-bla U2OS cells• Tango™ GPR120S-bla U2OS cell Assay Protocol• Certificate of AnalysisThe Tango™ GPR120S-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Gene Symbol

GPR120S

Population Status

Single Cell Clone Origin

Quantity

8 x 106Cells

Target Entry

GPR120S

Cell Line

U2OS

Druggable Target

GPCR

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Description

  • Tango™ GPR120 (short)-bla U2OS cells contain the human GPR120 (short) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element
  • The Tango™ GPR120 (short)-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of GW9508 (Figure 1)
  • In addition, Tango™ GPR120 (short)-bla U2OS cells have been tested for assay performance under variable conditions.