Ciclosporin for system suitability A
European Pharmacopoeia (EP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 59865-13-3
Synonym(S): Cyclosporin A, Antibiotic S 7481F1, Cyclosporine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | Y0002292-1-MG | In Stock | ₹ 14,970.98 |
Y0002292 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 14,970.98
GST (18%): ₹ 2,694.776
Total Price: ₹ 17,665.756
API family
ciclosporin
manufacturer/tradename
EDQM
application(s)
pharmaceutical
storage temp.
2-8°C
SMILES string
CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
InChI
1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
InChI key
PMATZTZNYRCHOR-CGLBZJNRSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Sigma Aldrich Fine Chemicals Biosciences Ciclosporin European Pharmacopoeia (EP) Reference Standard | 59865-13-3 | MFCD00274558 | | -- | ₹ 24,531.07 | ||
Cyclosporine Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™ | -- | ₹ 24,074.50 | ||
Sigma Aldrich Fine Chemicals Biosciences Cyclosporin A | 59865-13-3 | MFCD00274558 | 5mg | -- | ₹ 32,925.55 | ||
Sigma Aldrich Fine Chemicals Biosciences Cyclosporin A, Ready Made Solution 1 mg/mL in DMSO (0.2 μm-filtered) | 59865-13-3 | 1ml | -- | ₹ 17,880.10 | ||
eMolecules Medchem Express / Cyclosporin A / 100mg / 446273016 / HY-B0579 / / 59865-13-3 / MFCD00274558 / 1202.635 / C62H111N11O12 | -- | ₹ 7,860.48 | ||
Enzo Life Sciences Cyclosporin A (500mg). CAS: 59865-13-3 | -- | ₹ 31,626.15 | ||
Cyclosporine | -- | ₹ 18,175.18 | ||
Cyclosporin A solution | -- | ₹ 27,038.90 | ||
Cyclosporine | -- | ₹ 1,51,182.00 | ||
Ciclosporin | -- | ₹ 16,516.80 |
Related Products
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
- Application: Ciclosporin for system suitability A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
- Biochem/physiol Actions: A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.
- Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Repr. 1B
WGK
WGK 3