700024P

7α,27-dihydroxycholesterol

Manufacturer: Sigma Aldrich

CAS Number: 4725-24-0

Synonym(S): 111116

Select a Size

Pack Size SKU Availability Price
1 MG 700024P-1-MG In Stock ₹ 34,715.78

700024P - 1 MG

₹ 34,715.78

In Stock

Quantity

1

Base Price: ₹ 34,715.78

GST (18%): ₹ 6,248.84

Total Price: ₹ 40,964.62

form

powder

packaging

pkg of 1 × 1 mg (700024P-1mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C27H46O3/c1-17(16-28)6-5-7-18(2)21-8-9-22-25-23(11-13-27(21,22)4)26(3)12-10-20(29)14-19(26)15-24(25)30/h15,17-18,20-25,28-30H,5-14,16H2,1-4H3/t17?,18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1

InChI key

RXMHNAKZMGJANZ-DTTSCKGMSA-N

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Description

  • General description: 7α,27-dihydroxycholesterol (7α,27-di-OHC) is an oxysterol with oxidized side chains.[1] 7α,27-dihydroxycholesterol (7α27-OHC) is synthesized by the hydroxylation of 27-Hydroxycholesterol (27-OHC) and is a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC).[2]
  • Biochem/physiol Actions: 7α,27-dihydroxycholesterol (7α,27-di-OHC) is one of the metabolite screened in pathological conditions such as neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human specimens.[3] Upon the lipopolysaccharide activation, the levels of 7α,27-di-OHC decreases.[1]7α27-OHC is a ligand for Epstein-Barr virus-induced gene 2 (EBI2).[2]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700024P-1mg)