860502P
C2 Ceramide (d18:1/2:0)
Manufacturer: Sigma Aldrich
CAS Number: 195194-58-2
Synonym(S): N-acetoyl-D-erythro-sphingosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 860502P-5-MG | In Stock | ₹ 12,557.00 |
860502P - 5 MG
In Stock
Quantity
1
Base Price: ₹ 12,557.00
GST (18%): ₹ 2,260.26
Total Price: ₹ 14,817.26
form
powder
packaging
pkg of 1 × 5 mg (860502P-5mg)
manufacturer/tradename
Avanti Polar Lipids 860502P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(C)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C20H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(24)19(17-22)21-18(2)23/h15-16,19-20,22,24H,3-14,17H2,1-2H3,(H,21,23)/b16-15+/t19-,20+/m0/s1
InChI key
BLTCBVOJNNKFKC-QUDYQQOWSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
195194-58-2 | N-acetoyl-D-erythro-sphingosine | -- | ₹ 16,198.00 |
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Description
- General description: C2 Ceramide (d18:1/2:0) is a short-chain ceramide. In general ceramides are synthesized by de novo pathway from palmitic acid via series of intermediates to ceramidein the presence of dihydroceramide Δ4-desaturase.[1]
- Application: C2 Ceramide (d18:1/2:0) has been used to treat protoplasts for reactive oxygen species generation[2] and as an substrate for sphingomyelin synthase 2 enzyme.[3] It is suitable for use as an exogenous supplement in hippocampal cell cultures for the production of 2-hydroxyeicosatetraenoic acid (12-(S)-HETE).[4]
- Biochem/physiol Actions: C2 ceramide inhibits the progression of human bronchocarcinoma by modulating the matrix metallopeptidases-2 levels. It also inhibits glioma invasion[5] and induces apoptosis in HT-29 and HCT-116 human colon cancer cells.[6] Treatment of myotubes with C2-ceramide leads to decrease in glucose uptake and glycogen synthesis.[1] C2 along with C6 ceramides induces insulin resistance in myoblastic C2C12 cell line and L6 myotubes.[7]
- Packaging: 5 mL Amber Glass Screw Cap Vial (860502P-5mg)
SAFETY INFORMATION
WGK
WGK 3