860541P

C8 Lactosyl(β) Ceramide (d18:1/8:0)

Manufacturer: Sigma Aldrich

CAS Number: 384842-72-2

Synonym(S): D-lactosyl-β-1,1′ N-octanoyl-D-erythro-sphingosine

Select a Size

Pack Size SKU Availability Price
5 MG 860541P-5-MG In Stock ₹ 29,638.85

860541P - 5 MG

₹ 29,638.85

In Stock

Quantity

1

Base Price: ₹ 29,638.85

GST (18%): ₹ 5,334.993

Total Price: ₹ 34,973.843

form

powder

packaging

pkg of 1 × 5 mg (860541P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860541P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI

1S/C38H71NO13/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-27(42)26(39-30(43)22-20-17-8-6-4-2)25-49-37-35(48)33(46)36(29(24-41)51-37)52-38-34(47)32(45)31(44)28(23-40)50-38/h19,21,26-29,31-38,40-42,44-48H,3-18,20,22-25H2,1-2H3,(H,39,43)/b21-19+/t26-,27+,28?,29?,31-,32?,33?,34?,35?,36+,37+,38-/m0/s1

InChI key

JUCWRRXMPGRQOG-WKSBFREFSA-N

Other Options

Image Product Name Manufacturer Price Range
LacCer d18:1/8:0
-- --
384842-72-2 | D-lactosyl--1,1' N-octanoyl-D-erythro-sphingosine
-- ₹ 1,04,931.00

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Description

  • General description: Lactosyl-ceramide is synthesized from complex glycosphingolipids by glucosylceramide synthase via caremide intermediate glucosylceramide.[1]
  • Application: C8 Lactosyl(β) Ceramide (d18:1/8:0) is suitable for use as a substrate for endoglycoceramidase II.[2] It is also suitable for use as a synthetic lipid standard for two-dimensional liquid chromatography−quadrupole time-of-flight mass spectrometry for lipid profiling[3] and lipidomic analysis.[4]
  • Biochem/physiol Actions: Lactosyl-β1-1′-N-octanoyl-D-erythro-sphingosine like other glycosphingolipids, stimulates caveolar endocytosis.[5] C8-LacCer mediates clustering of β1-integrins and actin cytoskeleton reorganization in skin fibroblasts.[6] High levels of lactosyl ceramide leads to decreased respiration leading to mitochondrial dysfunction.[1]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860541P-5mg)

SAFETY INFORMATION

WGK

WGK 3