Description

• General description: Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate, is an anionic surfactant widely used in various scientific applications, particularly in molecular biology, biochemical, and cell biology research. Its effectiveness stems from its amphiphilic nature, allowing it to interact with both hydrophobic and hydrophilic molecules. SDS is a versatile detergent that excels in solubilizing and denaturing proteins, making it an essential tool in protein extraction and purification procedures. By disrupting protein structures, SDS facilitates the separation of proteins based on their molecular weight during SDS-PAGE electrophoresis.Beyond protein analysis, SDS also finds applications in the electrophoretic separation of lipids, enabling the study and characterization of these important cellular components. Additionally, SDS is employed in various hybridization and molecular biology techniques, demonstrating its versatility across a range of research areas. SDS′s effectiveness in both ionic and anionic conditions further expands its utility, allowing it to adapt to diverse experimental setups and requirements. Its ability to unravel proteins by binding to peptide chains and imparting a negative charge effectively eliminates protein shape as a factor for gel separation, ensuring accurate protein size determination.
• Application: Sodium dodecyl sulfate has been used:in chromatin immunoprecipitationin SDS-polyacrylamide gel electrophoresis (SDS-PAGE)as a component of radioimmunoprecipitation assay buffer for immunoblotting
• Features and Benefits: Highly versatile surfactant for your molecular biology and biochemical researchSuitable for electrophoresis applicationsTested to confirm low levels of heavy metal contamination,ensuring suitability for various applications.
• Analysis Note: Tested for use in denatured polyacrylamide gel electrophoresis.
• Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research