901558
Lenalidomide
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 191732-72-6
Synonym(S): 1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole, 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 Ligase ligand, Ligand for PROTAC® research
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 901558-100-MG | In Stock | ₹ 4,254.23 |
| 1 G | 901558-1-G | In Stock | ₹ 20,351.00 |
| 5 G | 901558-5-G | In Stock | ₹ 30,775.48 |
901558 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 4,254.23
GST (18%): ₹ 765.761
Total Price: ₹ 5,019.991
ligand
lenalidomide
Assay
≥95%
form
powder
reaction suitability
reagent type: ligand
mp
265-268 °C
storage temp.
2-8°C
SMILES string
O=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC=C3N
InChI
1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
InChI key
GOTYRUGSSMKFNF-UHFFFAOYSA-N
Other Options
Related Products
Description
- Application: Lenalidomide is a ligand demonstrated to bind the Cereblon (CRBN) protein. Lenalidomide, along with other thalidomide derivatives, are useful for constructing small molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. Explore protein degrader building blocks, E3 ligase ligand-linker conjugates that simplify the synthesis and library generation of PROTACs..
- Other Notes: Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationPortal: Building PROTAC® Degraders for Targeted Protein DegradationStructure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogsLenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cellsThe myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 1B - STOT RE 2
Target Organs
Blood
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable