SML2283

Lenalidomide

≥98% (HPLC), powder, cereblon binder

Manufacturer: Sigma Aldrich

CAS Number: 191732-72-6

Synonym(S): Lenalidomide, 1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole, 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidin-2,6-dione, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, CC 5013, CC-5013

Select a Size

Pack Size SKU Availability Price
100 MG SML2283-100-MG In Stock ₹ 6,559.95
250 MG SML2283-250-MG In Stock ₹ 14,732.83

SML2283 - 100 MG

₹ 6,559.95

In Stock

Quantity

1

Base Price: ₹ 6,559.95

GST (18%): ₹ 1,180.791

Total Price: ₹ 7,740.741

product name

Lenalidomide, ≥98% (HPLC)

ligand

lenalidomide

Assay

≥98% (HPLC)

form

powder

reaction suitability

reagent type: ligand

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC=C3N

InChI

1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)

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Description

  • Biochem/physiol Actions: Lenalidomide, a derivative of thalidomide, is an immunomodulatory agent that is approved drug for treatment of multiple myeloma. Apparently Lenalidomide is a ligand of ubiquitin E3 ligase cereblon that induces the enzyme to degrade the Ikaros transcription factors IKAROS family zinc finger 1 (IKZF1) and IKZF3. Lenalidomide possess pleiotropic antitumor effects.[1] It is used in the treatment of 5q-deletion associated myelodysplastic syndrome (del(5q)-MDS).[2]

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H360D,H373

Precautionary Statements

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B - STOT RE 2

Target Organs

Blood

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable