533910
Tocris Bioscience™ PFK 15
Manufacturer: Fischer Scientific
CAS Number: 4382-63-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 533910-Each-of-1 | In Stock | ₹ 19,001.50 |
533910 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 19,001.50
GST (18%): ₹ 3,420.27
Total Price: ₹ 22,421.77
Chemical Name or Material
PFK 15
Synonym
1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
Solubility
Soluble to 100mM in DMSO
Formula Weight
260.29
Product Type
Bioactive Small Molecule
CAS
4382-63-2
Quantity
10 mg
Molecular Formula
C17H12N2O
Physical Form
Solid
Purity
>99%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ PFK 15 | -- | -- | ||
Tocris Bioscience™ PFK 15 | -- | ₹ 79,477.00 | ||
Sigma Aldrich Fine Chemicals Biosciences PFK15 >=98% (HPLC) | 4382-63-2 | 25MG | -- | ₹ 52,225.20 |
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Description
- Description Originally reported to be a selective PFKFB3 inhibitor (IC50 = 207 nM); a more recent report failed to demonstrate activity in a PFKFB3 kinase assay
- Selective for PFKFB3 over a panel of 96 kinases
- Reduces glucose uptake and induces apoptosis in H522 lung adenocarcinoma and Jurkat T cell leukemia cells
- Suppresses glucose uptake and tumor growth, and inhibits metastasis of Lewis lung carcinoma cell xenografts in mice.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C