58-665-0

Tocris Bioscience™ PH 797804

Manufacturer: Fischer Scientific

CAS Number: 1358027-80-1

Select a Size

Pack Size SKU Availability Price
Each of 1 58-665-0-Each-of-1 In Stock ₹ 1,15,166.00

58-665-0 - Each of 1

₹ 1,15,166.00

In Stock

Quantity

1

Base Price: ₹ 1,15,166.00

GST (18%): ₹ 20,729.88

Total Price: ₹ 1,35,895.88

Chemical Name or Material

(-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide

Quantity

50 mg

Molecular Formula

C22H19BrF2N2O3

Purity

>98%

CAS

1358027-80-1

Target

p38 Inhibitors

Formula Weight

477.3

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ PH 797804
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Tocris Bioscience™ PH 797804
-- ₹ 27,545.50
1358027-80-1 | (S)-(-)-PH-797804
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Description

  • Potent and selective p38α/β inhibitor (IC50 values are 26 and 102 nM, respectively)
  • Exhibits >100-fold selectivity for p38α/β over 71 other kinases, enzymes and GPCRs, including p38γ, p38δ, JNK and ERK2
  • Inhibits LPS-induced TNFα production in U937 monocytes in vitro
  • Suppresses acute and chronic inflammatory responses in rat models of arthritis
  • Orally active
  • PH 797804 is the (-)-atropisomer, which is 100-fold more potent than its (+)-atropisomer.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C