68-925-0
Tocris™ RIPGBM
Manufacturer: Fischer Scientific
CAS Number: 355406-76-7
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 68-925-0-Each-of-1 | In Stock | ₹ 96,529.40 |
68-925-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 96,529.40
GST (18%): ₹ 17,375.292
Total Price: ₹ 1,13,904.692
Chemical Name or Material
N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Quantity
50 mg
Molecular Formula
C26H21FN2O3
Purity
98%
CAS
355406-76-7
Target
RIP Kinase Inhibitors
Formula Weight
7272
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris™ RIPGBM | -- | -- | ||
Tocris™ RIPGBM | -- | ₹ 22,919.28 | ||
eMolecules Medchem Express / RIPGBM / 5mg / 536983973 / HY-122910 / / 355406-76-7 / MFCD05670032 / 428.463 / C26H21FN2O3 | -- | ₹ 8,646.35 |
Related Products
Description
- RIPK2 modulator, pro-drug of cRIPGM
- cRIPGM binds RIPK2 (apparent Kd = 2.3 μM)
- Selectively induces apoptosis in glioblastoma multiforme cancer stem cell lines (EC50 is <500 nM)
- Five-fold selective for CSCs compared with control cell types
- Reduces the formation of a prosurvival RIPK2/ TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex
- Inhibits tumor formation and growth in vivo
- Orally bioavailable and brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C