586410

Tocris Bioscience™ Tolcapone

Manufacturer: Fischer Scientific

CAS Number: 134308-13-7

Select a Size

Pack Size SKU Availability Price
Each of 1 586410-Each-of-1 In Stock ₹ 11,365.30

586410 - Each of 1

₹ 11,365.30

In Stock

Quantity

1

Base Price: ₹ 11,365.30

GST (18%): ₹ 2,045.754

Total Price: ₹ 13,411.054

Chemical Name or Material

(3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone

Synonym

Tasmar, Ro 40-7592

Target

Catechol O-Methyltransferase (COMT) Inhibitors

Formula Weight

273.24

CAS

134308-13-7

Quantity

10 mg

Molecular Formula

C14H11NO5

Purity

>99%

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Description

  • COMT inhibitor
  • Inhibits both brain and peripheral COMT
  • Also binds transthyretin (TTR) with high affinity (Kd1 and Kd2 values are 21 and 58 nM, respectively)
  • Inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro
  • Stabilizes TTR in mice and humans in vivo
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C