63-131-0

Tocris™ A 33

Manufacturer: Tocris™

CAS Number: 915082-52-9

Select a Size

Pack Size SKU Availability Price
Each of 1 63-131-0-Each-of-1 In Stock ₹ 22,339.00

63-131-0 - Each of 1

₹ 22,339.00

In Stock

Quantity

1

Base Price: ₹ 22,339.00

GST (18%): ₹ 4,021.02

Total Price: ₹ 26,360.02

Chemical Name or Material

2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid

Quantity

10 mg

Formula Weight

387.88

Purity

98%

CAS

915082-52-9

Molecular Formula

C19H18ClN3O2S

Product Type

Inhibitor

Other Options

Image Product Name Manufacturer Price Range
Sigma Aldrich Fine Chemicals Biosciences A-33 >=98% (HPLC) | 915082-52-9 | 25MG
-- ₹ 46,564.80
Sigma Aldrich Fine Chemicals Biosciences A-33 >=98% (HPLC) | 915082-52-9 | 5MG
-- ₹ 11,774.70
eMolecules​ Medchem Express / PDE4B-IN-2 / 5mg / 632433182 / HY-115687 / / 915082-52-9 / [null] / 387.880 / C19H18ClN3O2S
-- ₹ 11,790.72
PDE4B-IN-2
-- ₹ 8,010.00 - ₹ 64,080.00
915082-52-9 | A 33
-- ₹ 2,136.00 - ₹ 40,940.00

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Description

  • A 33 is a potent and selective PDE4B inhibitor (IC50 = 15 nM); exhibits >100-fold selectivity for PDE4B over 4D
  • Regulates cAMP in inflammatory cells
  • Inhibits LPS-induced TNF-α production and neutrophil accumulation in mouse lungs
  • Reduces microglial and neutrophil activation, and improves behavioral deficits in a traumatic brain injury model in vivo
  • Also exhibits antidepressant-like effects
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C