65-865
Tocris Bioscience™ Targapremir 210
Manufacturer: Tocris Bioscience™
CAS Number: 1049722-30-6
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 65-865-Each-of-1 | In Stock | ₹ 33,965.96 |
65-865 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,965.96
GST (18%): ₹ 6,113.873
Total Price: ₹ 40,079.833
Chemical Name or Material
N-(3-Azidopropyl)-4-[3-[6-(4-methyl-1-piperazinyl)[2,6'-bi-1H-benzimidazol]-2'-yl]phenoxy]butanamide
Quantity
5 mg
Purity
98%
CAS
1049722-30-6
Molecular Formula
C32H36N10O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules Medchem Express / Targapremir-210 / 5mg / 506404065 / HY-15861 / / 1049722-30-6 / [null] / 592.708 / C32H36N10O2 | -- | ₹ 34,062.08 | ||
1049722-30-6 | Targapremir-210 | -- | ₹ 15,931.00 - ₹ 2,64,775.00 |
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Description
- Targapremir 210 inhibits formation of mature miR-210 (IC50 = 200 nM) by binding to Dicer binding site of the miR-210 hairpin precursor (Kd = 200 nM) and inhibits Dicer processing of the miRNA
- Decreases levels of miR-210 and HIF-1α mRNA, and induces apoptosis in MDA-MB-231 cells cultured under hypoxic conditions
- Reduces tumor expression of HIF-1α mRNA and miR-210, and tumor growth in a triple negative breast cancer mouse model.