70-645-0
Tocris™ Ruxolitinib
Manufacturer: Tocris™
CAS Number: 941678-49-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-645-0-Each-of-1 | In Stock | ₹ 31,595.00 |
70-645-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,595.00
GST (18%): ₹ 5,687.10
Total Price: ₹ 37,282.10
Chemical Name or Material
(3 R)-3-Cyclopentyl-3-[4-(7 H-pyrrolo[2,3-d]pyrimidin-4-yl)-1 H-pyrazol-1-yl]propanenitrile
Quantity
50 mg
Molecular Formula
C17H18N6
Purity
98%
CAS
941678-49-5
Target
JAK Kinase Inhibitors
Formula Weight
2323
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules Ambeed / (R)-3-(4-(7H-Pyrrolo[23-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile / 1mg / 491170939 / A272323 / / 941678-49-5 / [null] / 306.373 / C17H18N6 | -- | ₹ 2,422.58 | ||
Medchemexpress LLC HY-50856 100mg , Ruxolitinib CAS:941678-49-5 Purity:>98% | -- | ₹ 17,942.40 | ||
Medchemexpress LLC HY-50856 200mg , Ruxolitinib CAS:941678-49-5 Purity:>98% | -- | ₹ 29,156.40 | ||
Medchemexpress LLC HY-50856 50mg , Ruxolitinib CAS:941678-49-5 Purity:>98% | -- | ₹ 13,456.80 | ||
Ruxolitinib, Thermo Scientific™ | -- | ₹ 33,820.00 | ||
Enzo Life Sciences Ruxolitinib (10mg). CAS: 941678-49-5 | -- | -- | ||
Cayman Chemical Ruxolitinib, 941678-49-5, 10 mg | -- | ₹ 12,793.75 | ||
Selleck Chemical LLC Ruxolitinib (INCB018424) 100mg 941678-49-5 | -- | ₹ 82,592.00 | ||
Selleck Chemical LLC Ruxolitinib (INCB018424) 25mg 941678-49-5 | -- | ₹ 34,176.00 | ||
eMolecules Target Molecule Ruxolitinib 5mg 335407467 T1829 941678-49-5 MFCD12031592 306.373 C17H18N6 | -- | ₹ 6,943.78 |
Related Products
Description
- Ruxolitinib is a potent and selective JAK1/2 inhibitor (IC50 values are 3.3 and 2.8 nM, respectively)
- Exhibits selectivity for JAK1/2 over Tyk2 and JAK3 (∼6-fold and >130-fold, respectively)
- Exhibits no significant inhibition against a commercial panel of 26 additional kinases
- Inhibits JAK2V617F-mediated signaling and proliferation in Ba/F3 cells and HEL cells
- Increases survival rates in a JAK2V617F-driven mouse model
- Identified as targeting human host proteins that interact with SARS-CoV-2
- Orally bioavailable
- Phosphate salt (Cat
- No
- 7048) also available.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C