7082170

Tocris Bioscience™ ML 179

Selective liver receptor homolog 1 (LRH1) inverse agonist

Manufacturer: Fischer Scientific

CAS Number: 1883548-87-5

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Chemical Name or Material

ML 179

Synonym

3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione

Molecular Formula

C21H25F3N4O2

Physical Form

Crystalline Solid

Purity

>99%

CAS

1883548-87-5

Solubility

Soluble to 50mM in DMSO

Formula Weight

422.44

Product Type

Bioactive Small Molecule

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Description

  • Selective liver receptor homolog 1 (LRH1, NR5A2) inverse agonist (IC50 = 320 nM and maximum efficacy of 64% repression)
  • Exhibits >31-fold selectivity over SF1.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C