7082194
Tocris Bioscience™ QAQ Dichloride
Photoswitchable Nav, Kv and Cav channel blocker
Manufacturer: Fischer Scientific
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Chemical Name or Material
QAQ dichloride
Solubility
Soluble to 50mM in water
Molecular Formula
C28H44Cl2N6O2
Physical Form
Solid
Purity
>98%
Synonym
2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride
Target
Non-selective Cav Blockers
Formula Weight
567.59
Product Type
Bioactive Small Molecule
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Description
- Photoswitchable Nav, Cav and Kv channel blocker
- Blocks channels in the trans conformation
- Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm
- Normally membrane impermeant, but enters nociceptive neurons via ion channels activated by noxious stimuli, particularly TRPV1
- Exhibits optically reversible local anesthesia in rats.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C