7110874

Tocris Bioscience™ Vatalanib succinate

Potent VEGFR inhibitor; also aromatase inhibitor

Manufacturer: Fischer Scientific

CAS Number: 212142-18-2

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Chemical Name or Material

N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate

Synonym

CGP 79787D, PTK787/ZK222584

Molecular Formula

C20H15ClN4.C4H6O4

Purity

>99%

CAS

212142-18-2

Target

VEGF Receptor Inhibitors

Formula Weight

464.9

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ Vatalanib succinate
-- ₹ 62,873.16
Tocris Bioscience™ Vatalanib succinate
-- ₹ 15,073.04
212142-18-2 | Vatalanib Succinate
-- ₹ 4,183.00 - ₹ 12,727.00

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Description

  • Potent VEGFR inhibitor (IC50 values are 37 and 77 nM for VEGFR-2 and -1, respectively)
  • Inhibits proliferation, migration and survival of HUVECs in vitro and inhibits growth, vascularization and metastasis of tumors expressing VEGFR in mouse models
  • Also inhibits PDGFR-β, c-Kit and c-Fms
  • Potent aromatase inhibitor (IC50 = 50 nM)
  • Orally available.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C