7110901
Tocris Bioscience™ A 971432
Potent and selective S1P5 agonist
Manufacturer: Fischer Scientific
CAS Number: 1240308-45-5
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Chemical Name or Material
1-[[4-[(3,4-Dichlorophenyl)methoxy]phenyl]methyl]-3-azetidinecarboxylic acid
Target
Sphingosine-1-phosphate Receptor Agonists
Formula Weight
366.24
CAS
1240308-45-5
Molecular Formula
C18H17Cl2NO3
Purity
>99%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ A 971432 | -- | ₹ 19,624.50 | ||
Tocris Bioscience™ A 971432 | -- | ₹ 81,257.00 | ||
Sigma Aldrich Fine Chemicals Biosciences A-971432 >=95% (HPLC) | 1240308-45-5 | MFCD30182357 | 5MG | -- | ₹ 12,756.37 | ||
Sigma Aldrich Fine Chemicals Biosciences A-971432 >=95% (HPLC) | 1240308-45-5 | MFCD30182357 | 25MG | -- | ₹ 50,943.60 | ||
1240308-45-5 | 1-({4-[(3,4-dichlorophenyl)methoxy]phenyl}methyl)azetidine-3-carboxylic acid | -- | ₹ 2,581.00 - ₹ 30,527.00 |
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Description
- Potent and selective S1P5 agonist (EC50 values are 4.1 and 5.7 nM in cAMP and GTPγS assays, respectively)
- Exhibits 60-fold selectivity over S1P1, and >1,600-fold selectivity over S1P2-4, and a panel of 129 kinases and 79 receptors
- Improves blood-brain barrier integrity in vitro and reverses age-related cognitive decline in vivo
- Orally available.
SAFETY INFORMATION
- Recommended Storage : Store at Room Temperature