7110871
Tocris Bioscience™ GW 2580
Selective cFMS kinase inhibitor; orally bioavailable
Manufacturer: Fischer Scientific
CAS Number: 870483-87-7
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Chemical Name or Material
5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Target
Additional RTK Inhibitors
Formula Weight
366.41
CAS
870483-87-7
Molecular Formula
C20H22N4O3
Purity
>99%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ GW 2580 | -- | ₹ 19,713.50 | ||
Tocris Bioscience™ GW 2580 | -- | ₹ 81,880.00 | ||
MilliporeSigma™ Calbiochem™ cFMS Receptor Tyrosine Kinase Inhibitor | -- | ₹ 14,888.81 | ||
Medchemexpress LLC HY-10917 1g , GW2580 CAS:870483-87-7 Purity:98% | -- | ₹ 54,294.45 | ||
Sigma Aldrich Fine Chemicals Biosciences GW2580 >=98% (HPLC) | 870483-87-7 | 25MG | -- | ₹ 45,817.20 | ||
Sigma Aldrich Fine Chemicals Biosciences GW2580 >=98% (HPLC) | 870483-87-7 | 5MG | -- | ₹ 11,556.65 | ||
eMolecules GW2580 | 870483-87-7 | MFCD12024701 | 1g | -- | ₹ 55,225.39 | ||
Medchemexpress LLC HY-10917 10mg Medchemexpress, GW2580 CAS:870483-87-7 Purity:>98% | -- | ₹ 8,036.70 |
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Description
- Potent and selective cFMS kinase inhibitor (IC50 = 0.06 μM)
- Exhibits selectivity for cFMS kinase over 186 other kinases
- Inhibits CSF-1-induced growth of rat monocytes in vitro
- Also inhibits bone resorption in osteoclast cultures, as well as connective tissue and bone destruction in a rat adjuvant arthritis model
- Suppresses M-NFS-60 tumor cell growth in mice
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C